George Nicholas Papanicolaou was born in Kimi on the island of Euboea. It is near the southern town of Karystos known for the ancient physician Diokles of. Even at a young age, George Papanicolaou envisioned himself striving to live his life out on some large, important, but as yet undefined stage. After receiving his. Georgios Nikolaou Papanikolaou was a Greek pioneer in cytopathology and early cancer George Papanikolaou In he moved to Miami, Florida, to develop the Papanicolaou Cancer Research Institute at the University of Miami, but.

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However, Papanicolaou soon found appointment as assistant in the pathology department of New York Hospital, and in he became assistant in anatomy at Cornell Medical College. Other diagnostic tests based upon Papanicolaou’s methodology exfoliated cytology, the scraping, staining, and examination of cells from the test niicholas proved effective in screening for abnormalities in cells from other organs and systems. Moreover, the two techniques are different in their design.

[George Nicholas Papanicolaou].

Fromhe began to focus on the cytopathology of the human reproductive system. This fact was recounted by Papanikolaou. After graduation, Papanicolaou worked in the military as an assistant surgeon for a short time, then returned to his hometown, Kimi.

Born on May 13,in the town of Kimi pwpanicolaou the island of Euboea, Greece, Papanicolaou was one of four children. Upon examination of a slide made from a smear of the patient’s vaginal fluid, Papanicolaou discovered that abnormal cancer cells could be plainly observed under a microscope. Nikolas and Maria Papanicolaou.

However, his desire to work in science soon took hold and he travelled to the University of Munich in Germany, receiving a PhD in zoology in By January research had begun but unfortunately he suffered a heart attack in February and died, three months after moving to Miami. The study of science and medicine in Greece goes back as far as the history of medicine and was the home, in the late s, of Nikolas and Maria Papanicolaou a physician on the island of Euboea, Greece.

University of Athens University of Munich. En route to Paris, Papanicolaou stopped for a visit at the Oceanographic Institute of Monaco and accepted an unexpected offer to join its staff.


In countries where Pap smears are routine clinical practice, cervical cancer rates have dropped dramatically, and the screening test is credited as one of the greatest life-saving techniques in medical practice.

In female guinea pigs, Papanicolaou had already noticed cell transformation and wanted to corroborate the phenomenon in human females. Cite this article Pick a style below, and copy the text for your bibliography. Sign in with your library card. When his mother died inhe returned to Greece and served as an army physician during the Balkan War.

Parthenon Publishing Group; An eponym is a word derived from the name of a person, whether real or fictional. It happened that one of Papanicolaou’s human subjects was suffering from uterine cancer.

George Papanicolaou: Cytopathology, Cancer

Papanicolaou persisted with his ideas, and finally cytologic examination of the cervix was accepted. Life of George N. Arriving with little money and no arrangements for employment, both Papanicolaou and his wife were forced to take any job that they could get. The power of Papanicolaou screening for papsnicolaou cancer was remarkable.

Inhe graduated from medical school with top honours. Thus what was probably the first Pap smear — from a guinea pig. The paper and the Pap test proved to be a fundamental milestone in the treatment of a deadly cancer in teorge.

In female guinea pigs, Papanicolaou had already noticed cell transformation and wanted to corroborate the phenomenon in human females. It demonstrates the histological changes occurring in the vagina during the menstrual cycle. However, this potential medical breakthrough lapanicolaou initially met with skepticism and resistance from the medical community. A British researcher had shown that cancer cells could be identified in lung cancer papaniicolaou in the early s.

He was nicholxs when he was able to discern differences between the cytology of normal and malignant cervical cells upon a simple viewing of swabs smeared on microscopic slides. That honour goes to British physician Walter Hayle Walshe, who referred to this phenomenon in a book on lung diseases one century before.

His studies on human beings, fromwas done to a large degree in collaboration with the gynaecologist Herbert Frederick Traut Subscribe Access to the full content requires a subscription. For the next year he took care of patients at a leper colony north of his hometown of Kimi.


It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person. Unfortunately, Papanicolaou died within geeorge months of his arrival in Miami, suffering a fatal myocardial infarction on February 19, The institute papabicolaou renamed the Papanicolaou Cancer Research Institute in his honor.

After early schooling in Coumi, he attended Gymnasium in Athens and then studied medicine at the University of Athens. Archived from the original on 6 January Much of his work was done in collaboration with the biochemist Charles Rupert Stockard and E.

Journal List Singapore Med J v. These outcasts were socially isolated, and Papanicolaou gave them both medical and personal care with compassion and grace.

Moreover, such early diagnosis enabled physicians to treat patients while they were still in the earliest, and most treatable, stages of cancer.

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George Nicholas Papanicolaou was born on May 13,the third child of the couple who raised him and his two sisters in the small town of Kymi where he served as physician. He is best known for creating the Papanicolaou test, commonly known as the Pap smear, which revolutionised the early detection of cervical cancer. Retrieved from ” https: The young couple returned to Greece following the death of his mother. The simple procedure, now famously known as the Pap smear or test, quickly became the gold standard in screening for cervical cancer.

Any sale of the physical original does not include or convey the Copyright or any right comprised in the copyright. Pap’ Taken by Death”. In Papanikolaou told an incredulous audience of physicians about the noninvasive technique of gathering cellular debris from the lining of the nicohlas tract and smearing it on a glass slide for microscopic examination as a way to identify cervical cancer.

Recent papers have proven that Babes’s method was different from Papanicolaou’s and that the paternity of Pap test belongs solely to Papanicolaou.

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